Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Anti-Rat RT6.2 (Peripheral T Cells) Antibody, clone GY1/12    

Anti-Rat RT6.2 (Peripheral T Cells) Antibody, clone GY1/12

Rat Anti-Rat Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20974
Reactivity Rat
Host Rat
Clonality Monoclonal
Isotype IgG2c
Clone Names GY1/12
Calculated MW 31438 Da
Additional Information
Purification Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum
Immunogen Spleen and lymph node cells from F344 rats.
Shelf Life 18 months from date of despatch.
Gene ID 293152
Other Names T-cell ecto-ADP-ribosyltransferase 2,, ADP-ribosyltransferase C2 and C3 toxin-like 2, ARTC2, Alloantigen Rt6.2, Mono(ADP-ribosyl)transferase 2B, T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 2, T-cell mono(ADP-ribosyl)transferase 2, T-cell surface protein Rt6.2, Art2b, Rt6-b
Target/Specificity Rat anti-Rat RT6.2 antibody, clone GY1/12 recognizes rat T-cell ecto-ADP-ribosyltransferase 2, also known as Alloantigen Rt6.2, RT6.2, ADP-ribosyltransferase C2 and C3 toxin-like 2, ARTC2, Mono(ADP-ribosyl) transferase 2B or T-cell surface protein Rt6.2. RT6.2 is a 275 amino acid GPI anchored cell membrane protein belonging to the Arg-specific ADP-ribosyltransferase family. RT6.2 has an N-terminal 20 amino acid signal peptide sequence and 29 amino acid C-terminal propeptide region removed in the mature form.Rt6 is expressed exclusively by post-thymic T cells (Kochet al.1990) with RT6.2 alloantigen being expressed by RT6B rat strains incliuding BH.6B, BS,6B, LEW.6b and F334.6B (Kochet al.1988). Defects in the RT6 gene expression correlate with increased susceptibility for insulin dependent diabetes and other autoimmune diseases (Haaqet al.1996). Rat anti-Rat RT6.2 antibody, clone GY1/12 does not recognize the RT6.1 alloantigen expressed by post-thymic T-cells of RT6A rat strains including BUF, LEW and PVG. The RT6.1 alloantigen is recognized by the Rat anti-Rat RT6.1 antibody, clone P4/16.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat RT6.2 (Peripheral T Cells) Antibody, clone GY1/12 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


1. Butcher, G.W. (1987) A list of monoclonal antibodies specific for alloantigens of the rat.
J. Immunogenetics 14: 163-176. 2. Thiele, H.G. Koch, F., Hamann, A. and Arndt, R., (1986) Biochemical characterization of the T-cell alloantigen RT-6.2
Immunology 59: 195-201. 3. Koch, F., Haag, F., Kashan, A. and Thiele, H.G., (1990) Primary structure of rat RT6.2, a nonglycosylated phosphatidylinositol-linked surface marker of postthymic T cells.
Proc. Natl. Acad. Sci. U.S.A. 87: 964-967. 4. Takada, T., Lida, K. and Moss, J. (1994) Expression of NAD glycohydrolase activity by rat mammary adenocarcinoma cells transformed with rat T cell alloantigen RT6.2.
J. Biol. Chem. 269: 9420-9423. 5. O'Sullivan, N.L. et al. (2001) Lymphocyte lineages at mucosal effector sites: rat salivary glands.
J Immunol. 166: 5522-9. 6. Bell, E.B. et al. (1989) The origin of T cells in permanently reconstituted old athymic nude rats. Analysis using chromosome or allotype markers.
Immunology. 68: 547-56. 7. Orloff, S.L. et al. (2000) Tolerance induced by bone marrow chimerism prevents transplant vascular sclerosis in a rat model of small bowel transplant chronic rejection.
Transplantation. 69: 1295-303. 8. Koch, F. et al. (1988) The rat T-cell differentiation marker RT6.1 is more polymorphic than its alloantigenic counterpart RT6.2.
Immunology. 65: 259-65. 9. Fangmann, J. et al. (1991) Diabetes-prone BB rats express the RT6 alloantigen on intestinal intraepithelial lymphocytes.
Eur J Immunol. 21: 2011-5. 10. Rigby, M.R. et al. (1996) Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity.
J Immunol. 156: 4259-65. 11. Fangmann, J. et al. (1991) Unusual phenotype of intestinal intraepithelial lymphocytes in the rat: predominance of T cell receptor alpha/beta+/CD2- cells and high expression of the RT6 alloantigen.
Eur J Immunol. 21: 753-60.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# ABD11548
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
30% off on 2,800+ Neuroscience Antibodies. PromoCode:<span class=text-red> FLASH20
Terms & Conditions