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>   home   >   Products   >   Primary Antibodies   >   Anti-Rat MHC Class I RT1Au Antibody, clone NR3/31    

Anti-Rat MHC Class I RT1Au Antibody, clone NR3/31

Rat Anti-Rat Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Rat
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names NR3/31
Additional Information
Immunogen AO lymphoid cells
Shelf Life 18 months from date of despatch.
Target/Specificity Rat anti-Rat MHC Class I RT1Au antibody, clone NR3/31 recognizes the rat RT1Au MHC class I antigen expressed on rat strains including AO, LOU, WAG, WF and Ludwig Wistar (Fernandez and weeks 1988).Rat anti-rat MHC class I RT1Au antibody, clone NR3/31 has been used successfully for the typing of immunocompetent cells transplanted into allogenic hosts in rat models of graft vs. host disease (Francoiset al.2006)
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat MHC Class I RT1Au Antibody, clone NR3/31 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Howard, J. C. et al. (1979) Monoclonal antibodies as tools to analyze the serological and genetic complexities of major transplantation antigens.
Immunol. Rev. 47:139-174. 2. Backman-Petersson, E. et al. (2000) Self-MHC class Ia (RT1-An) protects cells co-expressing the activatory allogeneic MHC class Ib molecule (RT1-Eu) from NK lysis.
Int. Immunol. 12(6):843-850. 3. Dressel, R. et al. (2000) Heat shock protein 70 is able to prevent heat shock-induced resistance of target cells to CTL.
J. Immunol. 164:2362-2371. 4. Gurusinghe, C.J. et al. (1993) Immunohistochemical detection of strain-specific major histocompatibility complex class I antigens in paraffin-embedded rat osteochondral tissue.
Histochem J. 25: 140-3. 5. Brouha, P.C. et al. (2004) Lymphadenectomy prior to rat hind limb allotransplantation prevents graft-versus-host disease in chimeric hosts.
Transpl Int. 17: 341-50. 6. Ildstad,S. (2004) Methods of using CD8+/TCR- facilitating cells (FC) for the engraftment of purified hematopoietic stem cells (HSC)
Patent application Publication numberUS20040228845 A1

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Cat# ABD11555
(40 western blots)
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