|Application ||WB, IHC-F, FC, IP|
|Calculated MW||43330 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R|
|Target/Specificity||Mouse anti-Human CD123 antibody, clone 6H6 recognizes the Human IL-3 receptor alpha chain, also known asCD123. Mouse anti-Human CD123 antibody, clone 6H6 is useful for monitoring expression of the LI-3 receptor on activated endothelial cells, monocytes and eosinophils, sorting bone marrow progenitor cells and purification of basophils.Mouse anti-Human CD123 antibody, clone 6H6 does not neutralize the activity of the IL-3 receptor alpha chain.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD123 Antibody, clone 6H6 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Korpelainen, E. et al. (1993) The receptor for interleukin 3 is selectively induced in human endothelial cells by tumour necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration.Proc. Natl. Acad. Sci. USA 90: 11137-11141. 2. Shimizu, Y. et al. (2008) Interleukin-3 does not affect the differentiation of mast cells derived from human bone marrow progenitors. Immunol Invest.37: 1-17 3. Massone, C. et al. (2011) Immunophenotype of skin lymphocytic infiltrate in patients co-infected with Mycobacterium leprae and human immunodeficiency virus: a scenario dependent on CD8+ and/or CD20+ cells.Br J Dermatol. 165: 321-8.
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