|Application ||WB, IHC-F, FC, E|
|Calculated MW||15834 Da|
|Purification||Purified IgG prepared by affinity chromatography on protein G from tissue culture supernatant|
|Immunogen||Recombinant Mouse IL-4|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-4, IL-4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor, Lymphocyte stimulatory factor 1, Il4, Il-4|
|Target/Specificity||Rat anti-Mouse Interleukin-4 antibody, clone BVD4-1D11 recognizes natural and recombinant mouse IL-4. 99% pure by SDS-PAGE.Clone BVD4-1D11 is reported to neutralise IL-4 activity (Abramset al., 1992).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse Interleukin-4 Antibody, clone BVD4-1D11 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Abrams J. et al. (1992) Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.Immunol. Rev. 127:5-24. 2. Sander B. et al. (1993) Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining.J. Immunol. Methods 166:201-214. 3. Hochrein H. et al. (2000) Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells.J. Exp. Med. 192:823-833. 4. Pechova, J. et al. (2004) Effect of tick salivary gland extract on the cytokine production by mouse epidermal cells.Folia Parasitol (Praha). 51: 367-72. 5. Finkelman, F.D. et al. (2000) Stat6 regulation of in vivo IL-4 responses.J Immunol. 164: 2303-10. 6. Hochrein, H. et al. (2000) Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells.J Exp Med. 192: 823-33. 7. Urban, J.F. Jr. et al. (2000) Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T cell-dependent mechanism.J Immunol. 164: 2046-52. 8. Yang, Y.F. et al. (2000) Requirement for IFN-gamma in IL-12 production induced by collaboration between v(alpha)14(+) NKT cells and antigen-presenting cells.Int Immunol. 12: 1669-75. 9. Pechová, J. et al. (2004) Effect of tick salivary gland extract on the cytokine production by mouse epidermal cells.Folia Parasitol (Praha). 51: 367-72. 10. Roy, E. et al. (2008) Beneficial effect of anti-interleukin-4 antibody when administered in a murine model of tuberculosis infection.Tuberculosis (Edinb). 88: 197-202.
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