|Immunogen||Immunoaffinity purified feline CD4.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Cat CD4 antibody, clone vpg34 recognizes the feline homolog of the human CD4 antigen. CD4 is not expressed on feline monocytes.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Cat CD4 Antibody, clone vpg34 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Willett, B.J. et al. (1994) The generation of monoclonal antibodies recognising novel epitopes by immunisation with solid matrix antigen-antibody complexes reveals a polymorphic determinant on feline CD4.J. Immunol. Methods. 176: 213-220. 2. Campbell, D.J. et al. (2004) Age-related differences in parameters of feline immune status.Vet Immunol Immunopathol. 100: 73-80. 3. Campbell, D.J. et al. (2004) Insulin-like growth factor-I (IGF-I) and its association with lymphocyte homeostasis in the ageing cat.Mech Ageing Dev. 125: 497-505. 4. Veir, J.K. et al. (2007) Effect of supplementation with Enterococcus faecium (SF68) on immune functions incats.Vet Ther. 8: 229-38. 5. Freer, G. et al. (2008) Immunotherapy with internally inactivated virus loaded dendritic cells boosts cellular immunity but does not affect feline immunodeficiency virus infection course.Retrovirology. 5: 33. 6. Pistello, M. et al. (2010) Env-expressing autologous T lymphocytes induce neutralizing antibody and afford marked protection against feline immunodeficiency virus.J Virol. 84: 3845-56. 7. Willett, B.J. et al. (2007) Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand.J Virol. 81: 9665-79. 8. Reinero, C.R. et al. (2008) Adjuvanted rush immunotherapy using CpG oligodeoxynucleotides in experimental feline allergic asthma.Vet Immunol Immunopathol. 121: 241-50. 9. Carreño, A.D. et al. (2008) Loss of naïve (CD45RA+) CD4+ lymphocytes during pediatric infection with feline immunodeficiency virus.Vet Immunol Immunopathol. 121: 161-8. 10. Flynn, J.N. et al. (2002) Longitudinal analysis of feline leukemia virus-specific cytotoxic T lymphocytes: correlation with recovery from infection.J Virol. 76: 2306-15. 11. Hosie, M.J. et al. (2000) Vaccination with inactivated virus but not viral DNA reduces virus load following challenge with a heterologous and virulent isolate of feline immunodeficiency virus.J Virol. 74: 9403-11. 12. Hosie, M.J. et al. (2002) Evolution of replication efficiency following infection with a molecularly cloned feline immunodeficiency virus of low virulence.J Virol. 76: 6062-72. 13. Kraase, M. et al. (2010) Feline immunodeficiency virus env gene evolution in experimentally infected cats.Vet Immunol Immunopathol. 134: 96-106. 14. Milner, R.J. et al. (2004) Suppurative rhinitis associated with Haemophilus species infection in a cat.J S Afr Vet Assoc. 75: 103-7. 15. Novacco, M. et al. (2012) Protection from reinfection in"Candidatus Mycoplasma turicensis"-infected cats and characterization of the immune response.Vet Res. 43: 82. 16. Reche, A.Jr. et al. (2010) Cutaneous mycoflora and CD4:CD8 ratio of cats infected with feline immunodeficiency virus.J Feline Med Surg. 12: 355-8. 17. Willett, B.J. et al. (2013) Selective expansion of viral variants following experimental transmission of a reconstituted feline immunodeficiency virus quasispecies.PLoS One. 8: e54871.
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