|Calculated MW||26120 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||T-cell surface glycoprotein CD8 alpha chain, CD8a, CD8A|
|Target/Specificity||Mouse anti-Cat CD8 alpha/beta antibody, clone vpg9 recognizes the feline homolog of human CD8. Clone vpg 9 specifically recognizes an epitope associated with the alpha/beta complex of the CD8 heterodimer (Shimojimaet al.1998).|
|Preservative & Stabilisers||0.09% Sodium azide; Stabilising agent|
|Storage||Storage at +4ºC. DO NOT FREEZE.|
|Precautions||Anti-Cat CD8 Alpha/Beta Antibody, clone vpg9 (RPE) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Willett, B.J., and Callanan, J.J. (1995) The expression of leucocyte differentiation antigens in the feline immune system.P 3-15. In B.J. Willett and O.J. Jarrett (eds). Feline Immunology and Immunodeficiency. Oxford University Press, Oxford. 2. Callanan, J.J., Racz, P., Thompson, H. and Jarrett, O., (1993) Morphologic characterization of the lymph node changes in feline immunodeficiency virus infection as an animal model of AIDS.In P. Racz, N. L. Letvin, and J.C. Gluckman (eds)., Animal models of HIV and other retroviral infections. S. Karger, Basel, Switzerland. P. 115-136. 3. Shimojima, M. et al. (1998) Characterization of anti-feline CD8 monoclonal antibodies. Vet.Immunol. Immunopathol. 61: 17-23. 4. Veir, J.K. et al. (2007) Effect of supplementation with Enterococcus faecium (SF68) on immune functions incats.Vet Ther. 8: 229-38. 5. Pistello, M. et al. (2010) Env-expressing autologous T lymphocytes induce neutralizing antibody and afford marked protection against feline immunodeficiency virus.J Virol. 84: 3845-56. 6. Willett, B.J. et al. (2007) Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand.J Virol. 81: 9665-79. 7. de Oliveira Medeiros, S. et al. (2015) Follow-up on long-term antiretroviral therapy for cats infected with feline immunodeficiency virus.J Feline Med Surg. pii: 1098612X15580144. 8. Milner, R.J. et al. (2004) Suppurative rhinitis associated with Haemophilus species infection in a cat.J S Afr Vet Assoc. 75 (2): 103-7.
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