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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Mouse CD28 Antibody, clone 37.51.1    

Anti-Mouse CD28 Antibody, clone 37.51.1

Hamster Anti-Mouse Monoclonal Antibody

     
  • FC - Anti-Mouse CD28 Antibody, clone 37.51.1  ABD11574
    Staining of mouse spleen cells with Hamster anti Mouse CD28: Alexa Fluor®? 647
  • FC - Anti-Mouse CD28 Antibody, clone 37.51.1  ABD11574
    Staining of mouse spleen cells with Hamster anti Mouse CD28:FITC
  • FC - Anti-Mouse CD28 Antibody, clone 37.51.1  ABD11574
    Staining of mouse spleen cells with Hamster anti Mouse CD28: Alexa Fluor® 488
  • FC - Anti-Mouse CD28 Antibody, clone 37.51.1  ABD11574
    Staining of mouse spleen cells with Hamster anti Mouse CD28
  • FC - Anti-Mouse CD28 Antibody, clone 37.51.1  ABD11574
    Staining of mouse spleen cells with Hamster anti Mouse CD28: Biotin
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IP
Primary Accession P31041
Reactivity Mouse
Host Hamster
Clonality Monoclonal
Isotype IgG
Clone Names 37.51.1
Calculated MW 25243 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Mouse T lymphoma EL-4 cells.
Shelf Life 18 months from date of despatch.
Gene ID 12487
Other Names T-cell-specific surface glycoprotein CD28, CD28, Cd28
Target/Specificity Hamster anti-Mouse CD28 antibody, clone 37.51.1 recognizes murine CD28, an 80kDa cell surface glycoprotein that is expressed by most thymocyte subsets and by peripheral T-cells. Studies show that CD28 expression on thymocytes and splenic T-cells can be upregulated upon activation.Murine CD28 acts as a co-stimulatory signal and may play an important role in regulating the immune response of T-cells.Hamster anti-Mouse CD28 antibody, clone 37.51.1 has been reported to enhance cytokine production and T-cell proliferation in combination with TCR-mediated signals (Grosset al.1992).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD28 Antibody, clone 37.51.1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Kawasaki, H. et al. (1999) Increased c-Fos/activator protein-1 confers resistance against induction on antigen-specific T cell.
Int. Immnol. 11: 1873 - 1880. 2. Gross, G.A. et al. (1992) Identification and distribution of the co-stimulatory receptor CD28 in the mouse.
J. Immunol. 149: 380 - 388.

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Cat# ABD11574
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