|Application ||IHC-F, FC|
|Purification||Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum|
|Immunogen||in vivo stimulated, purified mouse B cells.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Rat anti-Mouse MHC Class II antibody, clone IBL-3/5 recognizes a monomorphic epitope on murine MHC Class II molecules., The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region.MHC class II molecules are expressed by dendritic cells, B-cells and macrophages.Rat anti-Mouse MHC Class II antibody, clone IBL-3/5 induces homotypic clustering of B cells in vitro (Balogh 1995 In 9th International Congress of Immunology, Abstract book p. 72. No. 422).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse MHC Class II Antibody, clone IBL-3/5 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Muller, T. et al. (2004) Tocopherol long chain fatty alcohols decrease the production of TNF-alpha and NO radicals by activated microglial cells.Bioorg Med Chem Lett.14: 6023-6. 2. Pazmany, T. et al. (2000) Effect of transforming growth factor-beta1 on microglial MHC-class II expression.J Neuroimmunol. 103: 122-30. 3. Himoudi, N. et al. (2007) Development of anti-PAX3 immune responses; a target for cancer immunotherapy.Cancer Immunol Immunother. 56: 1381-95.
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