|Application ||WB, E, IP|
|Calculated MW||19400 Da|
|Purification||Purified IgG prepared by affinity chromatography from tissue culture supernatant|
|Immunogen||E. coli expressed recombinant mouse IL-2|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-2, IL-2, T-cell growth factor, TCGF, Il2, Il-2|
|Target/Specificity||Rat anti-mouse IL-2, clone JES6-1A12recognizesmouse Interleukin-2. IL-2 is a cytokine required for T-cell proliferation.Rat anti-mouse IL-2, clone JES6-1A12 is reported to have neutralizing activity for IL-2 (Abramset al.1992) and Bihlet al.2010).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse Interleukin-2 Antibody, clone JES6-1A12 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Abrams, J.S. et al. (1992) Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10and IL-5 in clinical samples.Immunol. Rev. 127: 5-24. 2. Sander, B. et al. (1993) Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining.J. Immunol. Methods 166: 201-214. 3. Rigby S. et al. (2003) Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4 producing CD4+ - TNK cells and skews differentiation of immunocompetent donor CD4+ cells.Blood 101:2024-2032. 4. Eyles J. et al. (2002) Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1.J. Biol Chem 277:43735-43740. 5. Kitching A. et al. (2000) IL-18 has IL-12-independent effects in delayed-type hypersensitivity : studies in cell-mediated crescentic glomerulonephritis.J. Immunol. 165:4649-4657. 6. Bihl, F. et al. (2010) Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection.J Immunol. 185: 2174-81 7. Tachibana, M. et al. (2000) Coreceptor function of mutant human CD4 molecules without affinity to gp120 of human immunodeficiency virus.J Biol Chem. 275: 20288-94.
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