|Application ||WB, IHC-F, FC, E|
|Calculated MW||17492 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.|
|Immunogen||Purified CHO cell expressed recombinant human IL-4.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra, IL4|
|Target/Specificity||Rat anti-Human Interleukin-4 antibody, clone MP4-25D2 recognizes human Interleukin-4 (IL-4), also known as B-cell stimulatory factor 1, Binetrakin, Pitrakinra or Lymphocyte stimulatory factor 1. Interleukin-4 is a 153 amino acid ~17kDa cytokine involved in the activation of B cells, macrophages and monocytes (UniProt: P05112).Polymorphisms in the IL-4 gene are asociated with susceptibility to, and outcome of ischemic stroke (Marousiet al.2011).Rat anti-Human Interleukin-4 antibody, clone MP4-25D2 is reported to neutralize IL-4 activity (Abramset al.1992andCarvalhoet al.1994).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Interleukin-4 Antibody, clone MP4-25D2 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Krohn, A. et al. (1998) Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.J. Neurosci. 18: 8186-8197. 2. Kubota, M. et al. (1997) Oral immunization with Simian Immunodeficiency Virus p55 gag and cholera toxin elicits both mucosal IgA and systemic IgG immune responses in non human primates. J. Immunol. 158: 5321-5329. 2. Abrams, J. S. et al. (1992) Strategies of anti-cytokine monoclonal antibody development : Immunoassay of IL-10 and IL-5 in clinical samples.Immunol. Rev. 127: 5-24. 3. Patterson, B. et al. (2001) Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting women.J. Clin. Invest. 107: 287-294. 5. Carvalho, E. et al. (1994) Restoration of IFN-gamma production and lymphocyte proliferation in visceral leishmaniasis.J. Immunol. 152: 5949-5956.
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