|Application ||WB, IHC-F, E|
|Calculated MW||33117 Da|
|Immunogen||Synthetic peptide from human myelin basic protein sequence, phosphorylated on threonine 98|
|Shelf Life||18 months from date of despatch.|
|Other Names||Myelin basic protein, MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein, MBP|
|Target/Specificity||Mouse anti-Human MBP (pThr98) antibody, clone 98P/12 recognizes myelin basic protein that is phosphorylated on threonine 98, it does not recognize the non-phosphorylated protein.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human MBP (pThr98) Antibody, clone 98P/12 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Yon, M. et al. (1995) Preparation of a novel monoclonal antibody specific for myelin basic protein phosphorylated on Thr98.J. Neuroimmunol. 58: 121-129. 2. Yon, M. et al. (1996) Identification of a mitogen-activated protein kinase site in human myelin basic protein in situ.J. Neuroimmunol. 65: 55-59. 3. DeBruin, L.S. et al. (2005) Developmental partitioning of myelin basic protein into membrane microdomains.J Neurosci Res. 80: 211-25. 4. DeBruin, L.S. et al. (2006) Partitioning of myelin basic protein into membrane microdomains in a spontaneously demyelinating mouse model for multiple sclerosis.Biochem Cell Biol. 84: 993-1005. 5. Boggs, J.M. and Wang, H. (2004) Co-clustering of galactosylceramide and membrane proteins in oligodendrocyte membranes on interaction with polyvalent carbohydrate and prevention by an intact cytoskeleton.J Neurosci Res. 76: 342-55.
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