|Application ||FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Bovine CD1w3 antibody, clone CC43 recognises the bovine CD1w3 cell surface antigen, a ~44kDa molecule expressed as a heterodimer with beta 2 microglobulin.Bovine CD1w3 is expressed by immature cortical thymocytes but not by mature CD2+ or WC1+ cells in peripheral lymphoid tissues. It is also expressed by B cells, monocytes and subsets of dendritic cells. refinement of the binding specificity of Mouse anti-Bovine CD1w3 antibody, clone CC43 indicates that the antibody binds to the bovine CD1d molecule (Nguyen 2011). Bovine Cd1d binds short chain glycosphingolipids (Wanget al.2012).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Bovine CD1w3 Antibody, clone CC43 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Howard, C.J. et al. (1993) A new bovine leukocyte antigen cluster comprising two monoclonal antibodies, CC43 and CC118, possibly related to CD1.Vet Immunol Immunopathol. 39: 69-76. 2. Naessens, J. et al. (1993) Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants.Vet Immunol Immunopathol. 39 (1-3): 283-90. 3. Naessens, J. et al. (1997) Nomenclature and characterization of leukocyte differentiation antigens in ruminants.Immunol Today. 18 (8): 365-8. 4. Howard, C.J. & Naessens, J. (1993) Summary of workshop findings for cattle (tables 1 and 2).Vet Immunol Immunopathol. 39 (1-3): 25-47. 5. Nguyen, T.K. et al. (2013) The bovine CD1D gene has an unusual gene structure and is expressed but cannot present a-galactosylceramide with a C26 fatty acid.Int Immunol. 25: 91-8. 6. Van Rhijn, I. et al. (2006) The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d.J Immunol. 176: 4888-93. 7. Rhind, S.M. et al. (1996) Discrimination of two subsets of CD1 molecules in the sheep.Vet Immunol Immunopathol. 52: 265-70. 8. Gibson, A. et al. (2012) Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response.Dev Comp Immunol. 36: 332-41. 9. Goldfinch, N. et al. (2010) Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen.Vet Res. 41: 62. 10. Gunnes, G. et al. (2000) Accessory cell populations in draining lymph nodes of lambs in the elicitation phase of DNCB-induced contact hypersensitivity.Vet Immunol Immunopathol. 76: 75-88. 11. Jörundsson, E. (2000) Distribution of MHC-II and CD1 molecules in the skin of lambs and changes during experimentally-induced contact hypersensitivity.Vet Immunol Immunopathol. 74: 87-101.
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