|Application ||WB, IHC-F, FC, E|
|Calculated MW||30717 Da|
|Immunogen||Recombinant ovine IL-1 Beta|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-1 beta, IL-1 beta, IL1B|
|Target/Specificity||Mouse anti-Sheep Interleukin-1 beta antibody, clone 1D4 recognizes ovine interleukin-1 beta, and shows no cross-reactivity with ovine IL-6, IL-8, TNF alpha or MCP-1.Mouse anti-Sheep Interleukin-1 beta antibody, clone 1D4 demonstrates partial neutralizing activity of ovine IL-1 beta.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Sheep Interleukin-1 beta Antibody, clone 1D4 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Rothel, J.S. et al. (1997) Analysis of ovine IL-1 beta production in vivoandin vitro by enzyme immunoassay and immunohistochemistry.Vet. Immunol. Immunopathol. 57: 267-278. 2. Martoriati, A. & Gérard, N. (2003) Interleukin-1 (IL-1) system gene expression in granulosa cells: kinetics during terminal preovulatory follicle maturation in the mare. Reprod Biol Endocrinol. 1: 42-51. 3. Wenz, J.R. et al. (2010) Factors associated with concentrations of select cytokine and acute phase proteins in dairy cows with naturally occurring clinical mastitis. J Dairy Sci. 93: 2458-70. 4. Rinaldi, M. et al (2010) A sentinel function for teat tissues in dairy cows: dominant innate immune response elements define early response to E. colimastitis.Funct Integr Genomics. 10: 21-38. 5. Bougarn, S. et al. (2010) Muramyl dipeptide synergizes with Staphylococcus aureus lipoteichoic acid to recruit neutrophils in the mammary gland and to stimulate mammary epithelial cells.Clin Vaccine Immunol. 17 (11): 1797-809. 6. Bannerman, D.D. et al. (2004) Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection.Clin Diagn Lab Immunol. 11: 463-72. 7. Simojoki, H. et al. (2011) Innate immune response in experimentally induced bovine intramammary infection with Staphylococcus simulansandS. epidermidis.Vet Res. 42: 49. 8. Redondo, E. et al. (2014) Induction of interleukin-8 and interleukin-12 in neonatal ovine lung following experimental inoculation of bovine respiratory syncytial virus.J Comp Pathol. 150 (4): 434-48. 9. Karisnan K et al. (2015) Interleukin-1 Receptor Antagonist Protects against Lipopolysaccharide Induced Diaphragm Weakness in Preterm Lambs.PLoS One. 10 (4): e0124390. 10. Dernfalk, J. et al. (2007) The xMAP technique can be used for detection of the inflammatory cytokines IL-1beta, IL-6 and TNF-alpha in bovine samples.Vet Immunol Immunopathol. 118 (1-2): 40-9. 11. Leite, F. et al. (2005) Incubation of bovine PMNs with conditioned medium from BHV-1 infected peripheral blood mononuclear cells increases their susceptibility to Mannheimia haemolyticaleukotoxin.Vet Immunol Immunopathol. 103 (3-4): 187-93. 12. Jacobsen, S. et al. (2007) The cytokine response of circulating peripheral blood mononuclear cells is changed after intravenous injection of lipopolysaccharide in cattle.Vet J. 174 (1): 170-5. 13. Cox, R.A. et al. (2007) Production of pro-inflammatory polypeptides by airway mucous glands and its potential significance.Pulm Pharmacol Ther. 20 (2): 172-7. 14. Bannerman, D.D. et al. (2004) Characterization of the bovine innate immune response to intramammary infection with Klebsiella pneumoniae.J Dairy Sci. 87 (8): 2420-32. 15. Rainard P et al.(2008)Staphylococcus aureus lipoteichoic acid triggers inflammation in the lactating bovine mammary gland.Vet Res. 39 (5): 52. 16. Matthews, K. et al. (2007) The effect of gene gun-delivered pGM-CSF on the immunopathology of the vaccinated skin.Scand J Immunol. 65 (3): 298-307. 17. Xu, A. et al. (2015) The Ovine Fetal and Placental Inflammatory Response to Umbilical Cord Occlusions With Worsening Acidosis.Reprod Sci. pii: 1933719115580994.
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