|Application ||WB, FC, E|
|Calculated MW||23446 Da|
|Immunogen||Recombinant ovine IL-6.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-6, IL-6, IL6|
|Target/Specificity||Mouse anti-Sheep Interleukin-6 antibody, clone 4B6 recognizes ovine interleukin-6 (IL-6) and has also been reported to recognise recombinant human IL-6 and bovine IL-6 transfected cells.Mouse anti-Sheep Interleukin-6 antibody, clone 4B6 does not cross react with ovine IL-1 beta, IL-8, MCP-1 or TNF alpha.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Sheep Interleukin-6 Antibody, clone 4B6 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. McWaters, P. et al. (2000) Characterisation of monoclonal antibodies to ovine interleukin-6 and the development of a sensitive capture ELISA.Vet. Immunol. Immunopathol. 73: 155-165. 2. Wang, Z. et al. (2008) Acute hypercapnia improves indices of tissue oxygenation more than dobutamine in septic shock.Am J Respir Crit Care Med. 177: 178-83. 3. Su, F. et al (2007) Beneficial effects of ethyl pyruvate in septic shock from peritonitis.Arch Surg.142: 166-71. 4. Kabaroff, L. et al. (2006) Changes in ovine maternal temperature, and serum cortisol and interleukin-6 concentrations after challenge with Escherichia coli lipopolysaccharide during pregnancy and early lactation.J Anim Sci. 84: 2083-8. 5. Shashikant, B.N. et al. (2005) Dose response to rhCC10-augmented surfactant therapy in a lamb model of infant respiratory distress syndrome: physiological, inflammatory, and kinetic profiles.J Appl Physiol. 99: 2204-11. 6. Redondo, E. et al. (2014) Induction of interleukin-8 and interleukin-12 in neonatal ovine lung following experimental inoculation of bovine respiratory syncytial virus.J Comp Pathol. 150 (4): 434-48. 7. Karisnan, K .et al. (2015) Interleukin-1 Receptor Antagonist Protects against Lipopolysaccharide Induced Diaphragm Weakness in Preterm Lambs.PLoS One. 10 (4): e0124390. 8. Xu, A. et al. (2015) The Ovine Fetal and Placental Inflammatory Response to Umbilical Cord Occlusions With Worsening Acidosis.Reprod Sci. pii: 1933719115580994. 9. Dooley, L.M. et al. (2015) Effect of mesenchymal precursor cells on the systemic inflammatory response and endothelial dysfunction in an ovine model of collagen-induced arthritis.PLoS One. 10 (5): e0124144.
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