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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human CD8 Beta Antibody, clone 2ST8.5H7    

Anti-Human CD8 Beta Antibody, clone 2ST8.5H7

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10966
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 2ST8.5H7
Calculated MW 23722 Da
Additional Information
Other Species Cynomolgus Pr,Rh
Purification Purified IgG prepared from ascites
Immunogen Normal human T lymphocytes
Shelf Life 12 months from date of reconstitution.
Gene ID 926
Other Names T-cell surface glycoprotein CD8 beta chain, CD8b, CD8B, CD8B1
Target/Specificity Mouse anti-Human CD8 beta antibody, clone 2ST8.5H7 recognizes the human CD8 cell surface antigen. The antibody binds to the beta chain, recognising an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.CD8 molecules are composed of dimers of either alpha/alpha or alpha/beta polypeptide combinations. Both types of dimer may co-exist at the cell surface.
Preservative & Stabilisers 1% Bovine Serum Albumin;
Storage Storage at 4℃ or at -20℃.
PrecautionsAnti-Human CD8 Beta Antibody, clone 2ST8.5H7 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Terry, L.A. et al. (1990) Differential expression and regulation of the human CD8 alpha and CD8 beta chains.
Tissue Antigens 35: 82-91. 2. DiSanto, J.P. et al. (1991) Generation of anti-human CD8 beta specific antibodies using transfectants expressing mixed species CD8 heterodimers.
J. Immunol. Methods 141: 123-131. 3. de la Calle-Martin, O. et al. (2001) Familial CD8 deficiency due to a mutation in the CD8 alpha gene.
J Clin Invest. 108: 117-23. 4. Fry, T.J. et al. (2002) IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates.
Blood. 101: 2294-9. 5. Schmitz, J.E. et al (1998) Expression of the CD8alpha beta-heterodimer on CD8(+) T lymphocytes in peripheral blood lymphocytes of human immunodeficiency virus- and human immunodeficiency virus+ individuals.
Blood. 92: 198-206.

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Cat# ABD11619
(40 western blots)
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