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>   home   >   Products   >   Primary Antibodies   >   Anti-Pig CD144 Antibody, clone 123    

Anti-Pig CD144 Antibody, clone 123

Rat Anti-Pig Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O02840
Reactivity Pig
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names 123
Calculated MW 87546 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Porcine VE-cadherin/human IgG Fc fusion protein.
Shelf Life 18 months from date of despatch.
Gene ID 414737
Other Names Cadherin-5, Vascular endothelial cadherin, VE-cadherin, CD144, CDH5
Target/Specificity Rat anti-Pig CD144, clone 123 recognises a ~120-130 kDa a single pass type I membrane protein considered to be the porcine homologue of human CD144, also known as VE-Cadherin or Cadherin-5.VE-cadherin is expressed by endothelial cells and is important in cell-cell adhesion, tight junction integrity and vascular permeabiltiy (Tinsleyet al.1999). VE-Cadherin is highly susceptible to proteolytic degradation. Western blotting and immunofluorescence studies with Rat anti-pig CD144, clone 123 demonstrate rearangement and upregulation of VE-cadherin in porcine endothelial cells cultured as part of tissue engineered blood vessels under shear stress conditions rather than static conditions (Leeet al.2012).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Pig CD144 Antibody, clone 123 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Nasu, K. et al. (1999) Alpha-galactosyl-mediated activation of porcine endothelial cells: studies on CD31 and VE-cadherin in adhesion and signaling.
Transplantation. 68 (6): 861-7.1. Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39: 54.

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Cat# ABD11625
(40 western blots)
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