|Application ||WB, IHC-F|
|Calculated MW||87546 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Porcine VE-cadherin/human IgG Fc fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cadherin-5, Vascular endothelial cadherin, VE-cadherin, CD144, CDH5|
|Target/Specificity||Rat anti-Pig CD144, clone 123 recognises a ~120-130 kDa a single pass type I membrane protein considered to be the porcine homologue of human CD144, also known as VE-Cadherin or Cadherin-5.VE-cadherin is expressed by endothelial cells and is important in cell-cell adhesion, tight junction integrity and vascular permeabiltiy (Tinsleyet al.1999). VE-Cadherin is highly susceptible to proteolytic degradation. Western blotting and immunofluorescence studies with Rat anti-pig CD144, clone 123 demonstrate rearangement and upregulation of VE-cadherin in porcine endothelial cells cultured as part of tissue engineered blood vessels under shear stress conditions rather than static conditions (Leeet al.2012).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Pig CD144 Antibody, clone 123 is for research use only and not for use in diagnostic or therapeutic procedures.|
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