|Application ||IHC-F, FC, IP|
|Other Species||Hooded Seal,Raccoon|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Dog CD11c antibody, clone CA11.6A1 recognises the canine CD11c cell surface antigen, a member of the alpha integrin family. Canine CD11c is expressed by monocytes, granulocytes and by dendritic cells.Mouse anti-Dog CD11c, clone CA11.6A1 immunoprecipitates proteins of approximately 95 kDa, corresponding to the common β chain of the CD11/CD18 heterodimer and 150 kDa, the CD11c; chain from canine leukocyte preparations (Danilenkoet al.1992)|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Dog CD11c Antibody, clone CA11.6A1 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Danilenko, D.M. et al. (1992) Canine leukocyte cell adhesion molecules (LeuCAMS): characterization of the CD11/CD18 family.Tissue Antigens 40: 13-21. 2. Kang, J.W. et al. (2008) Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells.Stem Cells Dev. 17: 681-93. 3. Affolter, V.K. and Moore, P.F. (2002) Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs.Vet Pathol. 39: 74-83. 4. Bird, R.C. et al. (2008) An allogeneic hybrid-cell fusion vaccine against canine mammary cancer.Vet Immunol Immunopathol. 123: 289-304. 5. Catchpole, B. et al. (2002) Generation of blood-derived dendritic cells in dogs with oral malignant melanoma.J Comp Pathol. 126: 238-41. 6. Isotani, M. et al. (2006) Efficient generation of canine bone marrow-derived dendritic cells.J Vet Med Sci. 68: 809-14. 7. Liu, C.C. et al. (2008) Transient downregulation of monocyte-derived dendritic-cell differentiation, function, and survival during tumoral progression and regression in an in vivo canine model of transmissible venereal tumor.Cancer Immunol Immunother. 57: 479-91. 8. McDonough, S.P. and Moore, P.F. (2000) Clinical, hematologic, and immunophenotypic characterization of canine large granular lymphocytosis.Vet Pathol. 37: 637-46. 9. Wang, Y.S. et al. (2007) Characterization of canine monocyte-derived dendritic cells with phenotypic and functional differentiation.Can J Vet Res. 71: 165-74. 10. Mathes, M. et al. (2006) Evaluation of liposomal clodronate in experimental spontaneous autoimmune hemolytic anemia in dogs.Exp Hematol. 34: 1393-402. 11. Sanchez, M.A. et al. (2004) Organ-specific immunity in canine visceral leishmaniasis: analysis of symptomatic and asymptomatic dogs naturally infected with Leishmania chagasi.Am J Trop Med Hyg. 70: 618-24. 12. Ricklin Gutzwiller, M.E. et al. (2010) Comparative analysis of canine monocyte- and bone-marrow-derived dendritic cells.Vet Res. 41: 40. 13. Ibisch, C. et al. (2005) Functional canine dendritic cells can be generated in vitro from peripheral blood mononuclear cells and contain a cytoplasmic ultrastructural marker.J Immunol Methods. 298: 175-82. 14. Wang, Y.S. et al. (2008) Cytokine profiles of canine monocyte-derived dendritic cells as a function of lipopolysaccharide- or tumor necrosis factor-alpha-induced maturation.Vet Immunol Immunopathol. 118: 186-98. 15. Schwartz, M. et al. (2008) Selective CD11a upregulation on neutrophils in the acute phase of steroid-responsive meningitis-arteritis in dogs.Vet Immunol Immunopathol. 126: 248-55. 16. Pai, C.C. et al. (2011) Immunopathogenic behaviors of canine transmissible venereal tumor in dogs following an immunotherapy using dendritic/tumor cell hybrid.Vet Immunol Immunopathol. 139 (2-4): 187-99. 17. Figueiredo, M.M. et al. (2013) Expression of Toll-like Receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum.BMC Immunol. 14: 22. 18. Larsen, A.K. et al. (2013) Entry and elimination of marine mammal Brucella spp. by hooded seal (Cystophora cristata) alveolar macrophages in vitro.PLoS One. 8: e70186. 19. Heinrich, F. et al. (2015) Immunophenotyping of immune cell populations in the raccoon (Procyon lotor)Vet Immunol Immunopathol. Nov 3 [Epub ahead of print]
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