|Application ||IHC-F, FC, IP|
|Calculated MW||134277 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Squamous cell carcinoma|
|Shelf Life||18 months from date of despatch.|
|Other Names||Epidermal growth factor receptor, 22.214.171.124, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1|
|Target/Specificity||Rat anti-Human EGF Receptor antibody, clone ICR11 recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas.High level expression of EGFR is often associated with advanced disease and poor prognosis.Rat anti-Human EGF Receptor antibody, clone ICR11 binds to epitope C (Modjtahediet al.1993).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human EGF Receptor Antibody, clone ICR11 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
2. Modjtahedi, H. et al. (1993) The human EGF receptor as a target for cancer therapy: six new rat mAbs against the receptor on the breast carcinoma MDA-MB 468.Br J Cancer. 67: 247-53.
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