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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Anti-Human Cyclin D3 Antibody, clone DCS-22    

Anti-Human Cyclin D3 Antibody, clone DCS-22

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30281
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names DCS-22
Calculated MW 32520 Da
Additional Information
Other Species Dog
Immunogen Recombinant human cyclin D3.
Shelf Life 12 months from date of reconstitution.
Gene ID 896
Other Names G1/S-specific cyclin-D3, CCND3
Target/Specificity Mouse anti-Human Cyclin D3 antibody, clone DCS-22 recognizes human G1/S-specific cyclin-D3, also known as CCND3. Cyclin D3 is a 292 amino acid ~34kDa regulatory protein affecting the cell cycle during the G1/S transition. Cyclin D3 is expressed in the G1 phase of the cell cycle, but after cyclin D1.Mouse anti-Human Cyclin D3 antibody, clone DCS-22 has been used for the detection od cyclin D3 in canine tissues using immunofluorescence and western blotting (Depoortereet al.1998).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Storage at 4℃ or at -20℃.
PrecautionsAnti-Human Cyclin D3 Antibody, clone DCS-22 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Bartkova, J. et al. (1996) Abundance and subcellular localisation of cyclin D3 in human tumours.
Int. J. Cancer 65: 323-327. 2. Pertia, A. et al. (2009) Immunoreactivity of p27(Kip1), cyclin D3, and Ki67 in conventional renal cell carcinoma.
Int Urol Nephrol. 41: 243-9. 3. Nikoleishvili, D. et al. (2008) Expression of p27((Kip1)), cyclin D3 and Ki67 in BPH, prostate cancer andhormone-treated prostate cancer cells.
Int Urol Nephrol. 40: 953-9. 4. Giddabasappa, A. et al. (2011) Low-level gestational lead exposure increases retinal progenitor cell proliferation and rod photoreceptor and bipolar cell neurogenesis in mice.
Environ Health Perspect. 119:71-7. 5. Ott, M.M. et al. (1997) Cyclin D1 expression in mantle cell lymphoma is accompanied by downregulation of cyclin D3 and is not related to the proliferative activity.
Blood. 90: 3154-9. 6. Depoortere, F. et al. (1998) A requirement for cyclin D3-cyclin-dependent kinase (cdk)-4 assembly in the cyclic adenosine monophosphate-dependent proliferation of thyrocytes.
J Cell Biol. 140: 1427-39. 7. Van Keymeulen, A. et al. (1999) Cyclin D3 accumulation and activity integrate and rank the comitogenic pathways of thyrotropin and insulin in thyrocytes in primary culture.
Oncogene. 18: 7351-9.

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Cat# ABD11652
(40 western blots)
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