|Application ||IHC-P, IHC-F|
|Calculated MW||51268 Da|
|Immunogen||Synthetic peptide derived from C-terminus of human cytokeratin 16.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Keratin, type I cytoskeletal 16, Cytokeratin-16, CK-16, Keratin-16, K16, KRT16, KRT16A|
|Target/Specificity||Mouse anti-Human Cytokeratin 16 antibody, clone LL025 recognizes human cytokeratin 16, expressed in areas where there is high turnover of keratinocytes.Cytokeratin 16 expression is particularly pronounced in conditions such as wound healing, psoriasis and also in some carcinomas such as basal cell carcinoma.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Cytokeratin 16 Antibody, clone LL025 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Markey, A.C. et al. (1992) Keratin expression in basal cell carcinomas.Br. J. Dermatol. 126: 154-160. 2. Wetzels, R.H.W. et al. (1991) Basal cell-specific and hyperproliferation related keratins in human breast cancer.Am. J. Pathol. 138: 751-763. 3. Méndez, E. et al. (2007) Tumor-specific genetic expression profile of metastatic oral squamous cell carcinoma. Head Neck. 29: 803-14. 4. de Breij, A. et al. (2012) Three-Dimensional Human Skin Equivalent as a Tool To Study Acinetobacter baumannii Colonization.Antimicrob Agents Chemother. 56: 2459-64. 5. Kvist, P.H. et al. (2009) Comparison of the effects of vitamin D products in a psoriasis plaque test and a murine psoriasis xenograft model.J Transl Med. 7: 107. 6. Lago, E. et al. (2007) Clinical and immunohistochemical assessment of the effect of cyclosporin in keratinocytes and dermal dendrocytes in psoriasis.J Cutan Pathol. 34: 15-21. 7. Rikimaru, K. et al. (1997) Correlation between hyperproliferation and suprabasal integrin expression in human epidermis reconstituted in culture.Exp Dermatol. 6: 214-21. 8. Li, A. et al. (2004) Extensive tissue-regenerative capacity of neonatal human keratinocyte stem cells and their progenyJ Clin Invest. 113: 390-400.
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