|Application ||WB, IHC-P, E|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Shelf Life||18 months from date of despatch.|
|Other Names||Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3|
|Target/Specificity||Mouse anti-hCG antibody, clone INN-hCG-2 recognizes the beta 1 epitope on human chorionic gonadotrophin (hCG).Chorionic gonadotrophin is a member of the glycoprotein hormone family that is synthesized by the placenta throughout pregnancy. The glycoprotein hormone family has 4 members, the other three being luteinising hormone (LH), follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH). All consist of two subunits, alpha and beta. The alpha subunit is highly homologous between family members.Mouse anti-hCG antibody, clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-hCG (Beta 1 Epitope) Antibody, clone INN-hCG-2 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kofler, R. et al. (1982) Monoclonal antibodies against human chorionic gonadotropin (hCG): I. Production, specificity, and intramolecular binding sites. Am. J. Reprod. Immunol. 2: 212-216. 2. Berger, P. et al. (1993) Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies.J. Clin. Endocrinol. Metab. 77: 347-351. 3. Zimmermann, G. et al. (2009) Zimmermann G, Ackermann W, Alexander H. Epithelial human chorionicEpithelial human chorionic gonadotropin is expressed and produced in human secretory endometrium during the normal menstrual cycle. Biol Reprod. 2009 May;80(5):1053-65. Epub 2009 Jan 21.PubMed PMID: 19164178.Biol Reprod. 80:1053-65. 4. Zimmermann, G. et al. (2003) Expression of beta hCG and alpha CG mRNA and hCG hormone in human decidual tissue in patients during tubal pregnancy.Mol Hum Reprod. 9: 81-9. 5. Charrel-Dennis, M. et al. (2005) The human chorionic gonadotropin-beta arginine68 to glutamic acid substitution fixes the conformation of the C-terminal peptide.Mol Endocrinol. 19: 1803-11.
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