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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Anti-Human Cdk6 Antibody, clone DCS-83.1    

Anti-Human Cdk6 Antibody, clone DCS-83.1

Mouse Anti-Human Monoclonal Antibody

  • WB - Anti-Human Cdk6 Antibody, clone DCS-83.1  ABD11673
    Western blot analysis of Molt-4 acute lymphoblastic derived T-cell lysate probed with Mouse anti Human Cdk6 antibody followed by HRP conjugated Goat anti Mouse IgG, visualized by chemiluminescence
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q00534
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names DCS-83.1
Calculated MW 36938 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A/G
Immunogen Recombinant cdk6 protein
Shelf Life 18 months from date of despatch.
Gene ID 1021
Other Names Cyclin-dependent kinase 6,, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE, CDK6, CDKN6
Target/Specificity Mouse anti-Human Cdk6 antibody, clone DCS-83 recognizes the human cyclin dependent kinase 6, also known as Cdk6 or Serine/threonine-protein kinase PLSTIRE. Cdk6 is a 326 amino acid member of the CDC2/CDKX subfamily containing a single protein kinase domain. Pck6 migrates at ~37kDa in Western blotting under reducing conditions. Cdk6 pays an important role in cell cycle progression from the G1 to S phase (Sunet al.2008)Mouse anti-Human Cdk6, clone DCS83 additionally recognizes both the rat and mouse homologs of Human Cdk6. and has been successfully used for immunoprecipitation and immunofluorescesnce on acetone/methanol fixed cell preparations (Lukaset al.1999).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Cdk6 Antibody, clone DCS-83.1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Lukas, C. et al. (1999) Immunohistochemical analysis of the D-type cyclin-dependent kinases Cdk4 and Cdk6, using a series of monoclonal antibodies.
Hybridoma. 18: 225-34. 2. Tsubari, M. et al. (1999) Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity.
Mol Cell Biol. 19: 3654-63.1. Elledge, S.J. (1996) Cell Cycle Checkpoints: Preventing an identity crisis.
Science 274: 1664-1672.

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Cat# ABD11673
(40 western blots)
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