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>   home   >   Products   >   Primary Antibodies   >   Anti-Dog MHC Class II Monomorphic Antibody, clone CA2.1C12    

Anti-Dog MHC Class II Monomorphic Antibody, clone CA2.1C12

Mouse Anti-Dog Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Dog
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names CA2.1C12
Additional Information
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti-Dog MHC Class II Monomorphic antibody, clone CA2.1C12 recognizes a monomorphic epitope on canine MHC Class II which was classified at the First Canine Leucocyte Antigen Workshop (CLAW) [Cobboldet al.1992]. In dogs, MHC Class II is expressed by all peripheral blood mononuclear cells.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In dogs, this is referred to as the dog leukocyte antigen (DLA) region.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Dog MHC Class II Monomorphic Antibody, clone CA2.1C12 is for research use only and not for use in diagnostic or therapeutic procedures.
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1. Cobbold, S. & Metcalfe, S. (1994) Monoclonal antibodies that define canine homologues of human CD antigens: Summary of the First International Canine Leukocyte Antigen Workshop (CLAW).
Tissue Antigens 43: 137-154. 2. Wang, Y.S. et al. (2007) Characterization of canine monocyte-derived dendritic cells with phenotypic andfunctional differentiation. PubMed PMID:
Can J Vet Res. 71: 165-74. 3. Veenhof, E.Z. et al. (2011) Characterisation of T cell phenotypes, cytokines and transcription factors in the skin of dogs with cutaneous adverse food reactions.
Vet J. 187 (3): 320-4. 4. Caniatti, M. et al. (1996) Canine lymphoma: immunocytochemical analysis of fine-needle aspiration biopsy.
Vet Pathol. 33: 204-12. 5. Huang, Y.C. et al. (2008) CD5-low expression lymphocytes in canine peripheral blood show characteristics of natural killer cells.
J Leukoc Biol. 84: 1501-10. 6. Isotani, M. et al. (2006) Efficient generation of canine bone marrow-derived dendritic cells.
J Vet Med Sci. 68: 809-14. 7. Liu, C.C. et al. (2008) Transient downregulation of monocyte-derived dendritic-cell differentiation, function, and survival during tumoral progression and regression in an in vivo canine model of transmissible venereal tumor.
Cancer Immunol Immunother. 57: 479-91. 8. McDonough, S.P. and Moore, P.F. (2000) Clinical, hematologic, and immunophenotypic characterization of canine large granular lymphocytosis.
Vet Pathol. 37: 637-46. 9. Pumarola, M. et al. (2004) Canine inflammatory myopathy: analysis of cellular infiltrates.
Muscle Nerve. 29: 782-9. 10. Ricklin, Gutzwiller. M.E. et al. (2010) Comparative analysis of canine monocyte- and bone-marrow-derived dendritic cells.
Vet Res. 41: 40. 11. Yuasa, K. et al. (2007) Injection of a recombinant AAV serotype 2 into canine skeletal muscles evokes strong immune responses against transgene products.
Gene Ther. 14: 1249-60.

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Cat# ABD11680
(40 western blots)
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