|Calculated MW||149715 Da|
|Immunogen||Human lung CD143 (Angiotensin converting enzyme).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Angiotensin-converting enzyme, ACE, 3.2.1.-, 126.96.36.199, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1|
|Target/Specificity||Mouse anti-Human CD143 antibody, clone i2H5 recognizes human CD143, also known as angiotensin - converting enzyme (ACE). CD143 exists in two forms, a 170 kDa somatic form and a 90 kDa germinal form. The somatic form is expressed by endothelial cells (especially those of arterioles and lung capillaries), epithelial cells (especially in proximal renal tubules and in the small intestine), by some neuronal cells and variably on some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.Mouse anti-Human CD143 antibody, clone i2H5 recognizes active ACE binding to an N-terminal domain epitope different to that recognized by clone 9B9 (MCA2057).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Human CD143 Antibody, clone i2H5 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Danilov, S. et al. (1994) Structure-function analysis of angiotensin I-converting enzyme using monoclonal antibodies. Selective inhibition of the amino-terminal active site.J Biol Chem. 269 (43): 26806-14. 2. Metzger, R. et al. (2000) CD143 in the development of atherosclerosis. Atherosclerosis 150: 21 - 31.
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