|Application ||WB, IHC-P, FC, E|
|Calculated MW||28857 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Synthetic peptide corresponding to amino acids 198-208 of rat aquaporin 1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Aquaporin-1, AQP-1, Aquaporin-CHIP, Water channel protein for red blood cells and kidney proximal tubule, Aqp1, Chip28|
|Target/Specificity||Mouse anti-Aquaporin 1 antibody, clone 7D11 recognizes an epitope within an extracellular region of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28)Aquaporin 1 is a 28kDa integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kDa in mass.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Aquaporin 1 Antibody, clone 7D11 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Nagy, G. et al. (2002) Development and characterisation of a monoclonal antibody family againstaquaporin 1 (AQP1) and aquaporin 4 (AQP4).Pathol. Oncol. Res. 8: 115-124. 2. Bodis, B. et al. (2001) Active water selective channels in the stomach: investigation of aquaporins after ethanol and capsaicin treatment in rats. J. Physiol. 95: 271-275. 3. Felszeghy, S. et al. (2004) Expression of aquaporin isoforms during human and mouse tooth development.Arch Oral Biol. 49: 247-57. 4. Cabral, P.D and Herrera, M. (2012) Membrane-associated aquaporin-1 facilitates osmotically driven water flux across the basolateral membrane of the thick ascending limb.Am J Physiol Renal Physiol. 303: F621-9.
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