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Cartilage Oligomeric Matrix Protein Antibody, clone MA37C94 (HC484D1) (Monoclonal Antibody)

Rat Anti-Human Monoclonal Antibody

  • WB - Cartilage Oligomeric Matrix Protein Antibody, clone MA37C94 (HC484D1) (Monoclonal Antibody)  ABD11725
    Western blot analysis of recombinant Human cartilage oligomeric matrix protein probed with Rat anti Human Cartilage Oligomeric Matrix Protein follwed by Goat anti Rat IgG:HRP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49747
Reactivity Human
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names MA37C94 (HC484D1)
Calculated MW 82860 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Human cartilage derived COMP.
Shelf Life 18 months from date of despatch.
Gene ID 1311
Other Names Cartilage oligomeric matrix protein, COMP, Thrombospondin-5, TSP5, COMP
Target/Specificity Rat anti-Human cartilage oligomeric matrix protein, antibody, clone MA37C94 recognies human cartilage oligomeric matrix protein (COMP), otherwize known as Thrombospondin-5 (TSP-5). COMP is a 757 amino acid ~:100 kDa matrix glycoprotein bearing four EGF-like domains, a single TSP C-terminal do,aim and eight TSP type-3 repeats (Uniprot P49747). Defects in the COMP gene can lead to the presence of Pseudoachondroplasia (Poseyet al.2014) or Multiple epiphyseal dysplasia ( anti-Human cartilage oligomeric matrix protein antibody, clone at anti-Human cartilage oligomeric matrix protein, clone MA37C94 recognizes an epitope located in the central portion of the molecule.Rat anti-Human cartilage oligomeric matrix protein, antibody, clone MA37C94 has been described as suitable for use in western blotting (Gagarinaet al.2008) and immunohistochemistry (Grigoriadiset al.2006)
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsCartilage Oligomeric Matrix Protein Antibody, clone MA37C94 (HC484D1) (Monoclonal Antibody) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Grigoriadis, al. (2006) Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data.
Breast Cancer Res. 8: R56. 2. Milz, S. et al. (2007) An immunohistochemical study of the triangular fibrocartilage complex of the wrist: regional variations in cartilage phenotype.
J Anat. 211: 1-7. 3. Gagarina, V. et al. (2008) Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins.
J Biol Chem 283: 648-59. 4. Jäger, M. et al. (2006) Ovine cord blood accommodates multipotent mesenchymal progenitor cells.
In Vivo. 20: 205-14.

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Cat# ABD11725
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