Anti-Rat Calcitonin Receptor (C1B Isoform) Antibody, clone 21/00-A3-14-13
Mouse Anti-Rat Monoclonal Antibody
|Application ||IHC-P, E|
|Calculated MW||60292 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Synthetic peptide derived from sequence of rat calcitonin receptor.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Calcitonin receptor, CT-R, C1A/C1B, Calcr|
|Target/Specificity||Mouse anti-Rat calcitonin receptor antibody, clone 21/00-A3-14-13 recognizes the rat calcitonin receptor, a 482 amino acid ~55 kDa multi pass transmembrane membrane glycoprotein with seven transmembrane domains that is coupled to G protein messenger systems. Clone 21/00 recognises an epitope within extracellular domain that is unique to the C1b isoform.Calcitonin receptor is expressed in kidney, central and peripheral nervous systems and on osteoclasts. It is also expressed in a number of tissues during the development of the embryo and may be important in foetal morphogenesis.Two isoforms of the rat calcitoni receptor produced by alternative splicing have been described. Mouse anti-Rat calcitonin receptor antibody, clone 21/00-A3-14-13 binds to the canonical isoform 1, binding to the truncated isoform 2 has not been evaluated (UniProt : P32214).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat Calcitonin Receptor (C1B Isoform) Antibody, clone 21/00-A3-14-13 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Tikellis, c. et al. (2003) Calcitonin receptor isoforms expressed in the developing rat kidney.Kidney International. 63: 416.
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