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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD150 Antibody, clone A12    

Anti-Human CD150 Antibody, clone A12

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD150 Antibody, clone A12  ABD11746
    Staining of human peripheral blood monocytes with Mouse anti Human CD150:FITC
  • FC - Anti-Human CD150 Antibody, clone A12  ABD11746
    Staining of human peripheral blood monocytes with Mouse anti Human CD150
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13291
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names A12
Calculated MW 37231 Da
Additional Information
Other Species Cynomolgus Pr
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Activated human peripheral blood mononuclear cells.
Shelf Life 18 months from date of despatch.
Gene ID 6504
Other Names Signaling lymphocytic activation molecule, CDw150, IPO-3, CD150, SLAMF1, SLAM
Target/Specificity Mouse anti-Human CD150 antibody, clone A12 recognizes human CD150, a 70 kDa cell surface glycoprotein also known as signalling lymphocytic activation molecule (SLAM). CD150 is constitutively expressed on CD45+ ve T-cells, immature thymocytes, a subpopulation of peripheral B-cells and dendritic cells. CD150 is rapidly upregulated in T-cells, B-cells and dendritic cells after activation. In addition to the membrane form of CD150, activated T and B cells also express mRNA encoding a secreted form of CD150.Mouse anti-Human CD150 antibody, clone A12 is reported to induce proliferation of pre-activated T cells (Cockset al.1995).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD150 Antibody, clone A12 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Cocks, B.G. et al. (1995) A novel receptor involved in T-cell activation.
Nature. 376 (6537): 260-3. 2. Isomäki, P. et al. (1997) Increased expression of signaling lymphocytic activation molecule in patients with rheumatoid arthritis and its role in the regulation of cytokine production in rheumatoid synovium.
J Immunol. 159 (6): 2986-93. 3. Punnonen, J. et al. (1997) Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes.
J Exp Med. 185 (6): 993-1004. 4. Sayós, J. et al. (2001) Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP.
Blood. 97 (12): 3867-74. 5. Boussaad, I. et al. (2011) Wild-Type Measles Virus Interferes with Short-Term Engraftment of Human CD34+ Hematopoietic Progenitor Cells.
J Virol. 85: 7710-8. 6. García, V.E. et al. (2001) Signaling lymphocytic activation molecule expression and regulation in human intracellular infection correlate with Th1 cytokine patterns.
J Immunol. 167: 5719-24. 7. Mesman, A.W. et al. (2012) A prominent role for DC-SIGN+ dendritic cells in initiation and dissemination of measles virus infection in non-human primates.
PLoS One. 7: e49573.

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Cat# ABD11746
(40 western blots)
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