|Calculated MW||37822 Da|
|Immunogen||Recombinant human cathepsin B|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Cathepsin B, 188.8.131.52, APP secretase, APPS, Cathepsin B1, Cathepsin B light chain, Cathepsin B heavy chain, CTSB, CPSB|
|Target/Specificity||Mouse anti-Human Cathepsin B antibody, clone CB131 recognizes human cathepsing B, also known as APP secretase. Cathepsin B is a 399 amino acid lysosomal protease expressed in a wide range of tissues, including liver, skeletal muscle and heart. Cathepsin B is also expressed in human tumor tissues (Moinet al.1992).Cathepsin B plays a role in protein degradation and has also been shown to activate urokinase type plasminogen activator (Koboyashiet al.1991).Mouse anti-human cathepsin B antibody, clone CDB131 has been sussefully used to demonstrate the expression and localization of cathepsin B in human glioma tissue by immunohistochemistry and immunofluorescence techniques (Hayashiet al.2007).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Storage at 4℃ or at -20℃.|
|Precautions||Anti-Human Cathepsin B Antibody, clone CB131 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Hayashi, Y. et al. (2007) Regulation and function of aquaporin-1 in glioma cells.Neoplasia. 9: 777-87. 2. Farinati, F. et al. (1996) Increased levels of cathepsin B and L, urokinase-type plasminogen activator and its inhibitor type-1 as an early event in gastric carcinogenesis.Carcinogenesis. 17: 2581-7.
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