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Anti-Mouse CD71 Antibody, clone ER-MP21

Rat Anti-Mouse Monoclonal Antibody

Product Information
Primary Accession Q62351
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names ER-MP21
Calculated MW 85731 Da
Additional Information
Immunogen Balb/c macrophage precursor cell hybrids
Gene ID 22042
Other Names Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, CD71, Tfrc, Trfr
Target/Specificity Rat anti-Mouse CD71 antibody, clone ER-MP21 recognizes murine CD71, a 200kD antigen which is otherwise known as transferrin receptor. CD71 is expressed by all proliferating cell populations and exists as a homodimer at the cell surface.Clone ER-MP21 inhibits iron uptake and cell proliferation but does not compete with transferrin for binding to its receptor, which suggests that clone ER-MP21 binds to an epitope that is different from the transferrin-binding site (Leenenet al.1990).
PrecautionsAnti-Mouse CD71 Antibody, clone ER-MP21 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Leenen, P.J.M. et al. (1990) Differential inhibition of macrophage proliferation by anti-transferrin receptor antibody ER-MP21: correlation to macrophage differentiation stage.
Exp Cell Res.189:55 – 63. 2. Moos, T. (1995) Increased accumulation of transferrin by motor neurons of the mouse mutant progressive motor neuronopathy (pmn/pmn).
J Neurocytol. 1995 May;24(5):389-98.

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