|Application ||IHC-F, FC|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Isolated C3H thymic stromal cells|
|Shelf Life||12 months from date of reconstitution.|
|Target/Specificity||Rat anti-Mouse MHC Class II H-2I-Ak/D/B/Q/R antibody, clone ER-TR3 recognizes a polymorphic determinant of the mouse H-2I-A MHC class II antigen, reacting with haplotypes k, d, b, q and r. Mouse strains with the haplotypes s and f are not recognized by this antibody.Mouse MHC class II antigens are expressed by dendritic cells, B cells and macrophages. In thymus tissues, clone ER-TR3 stains cortical and medullary stromal cells.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse MHC Class II H-2I-Ak/D/B/Q/R Antibody, clone ER-TR3 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Huiskamp, R. et al. (1985) Repopulation of the mouse thymus after sublethal fission neutron irradiation: II. Sequential changes in the thymic microenvironment. J Immunol.134:2170 – 2178. 2. Van Vliet, E. (1985) Stromal cell types in the developing thymus of the normal and nude mouse embryo.Eur J Immunol.15:675 - 681.
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