|Application ||IHC-F, FC|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Isolated C3H thymic stromal cells|
|Shelf Life||12 months from date of reconstitution.|
|Target/Specificity||Rat anti-Mouse MHC Class II H-2I-Ak/D/B/Q/R antibody, clone ER-TR3 recognizes a polymorphic determinant of the mouse H-2I-A MHC class II antigen, reacting with haplotypes k, d, b, q and r. Mouse strains with the haplotypes s and f are not recognized by this antibody.Mouse MHC class II antigens are expressed by dendritic cells, B cells and macrophages. In thymus tissues, clone ER-TR3 stains cortical and medullary stromal cells.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse MHC Class II H-2I-Ak/D/B/Q/R Antibody, clone ER-TR3 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Huiskamp, R. et al. (1985) Repopulation of the mouse thymus after sublethal fission neutron irradiation: II. Sequential changes in the thymic microenvironment. J Immunol.134:2170 – 2178. 2. Van Vliet, E. (1985) Stromal cell types in the developing thymus of the normal and nude mouse embryo.Eur J Immunol.15:675 - 681.
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