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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Chicken Interferon alpha Antibody, clone UMCh3-IFNa    

Anti-Chicken Interferon alpha Antibody, clone UMCh3-IFNa

Mouse Anti-Chicken Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42165
Reactivity Chicken
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names UMCh3-IFNa
Calculated MW 22116 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Recombinant chicken Interferon alpha.
Shelf Life 18 months from date of despatch.
Gene ID 100857744;100857947;100858177;100859032;396398
Other Names Interferon type A1/A2, IFNA1
Target/Specificity ABD11784 recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. ABD11784 does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Chicken Interferon alpha Antibody, clone UMCh3-IFNa is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Sarmento, L. et al. (2008) Differential host gene expression in cells infected with highly pathogenic H5N1 avianinfluenza viruses.
Vet Immunol Immunopathol. 125: 291-302. 3. Schwarz, H. et al. (2004) Synthesis of IFN-beta by virus-infected chicken embryo cells demonstrated with specific antisera and a new bioassay.
J. Interferon Cytokine Res. 24: 179-184. 1. Staeheli, P. et al. (2001) Cytokines of Birds: Conserved functions – A largely different look.
J. Interferon Cytokine Res. 21: 993-1010.2. Sick, C et al. (1996) A family of genes coding for two serologically distinct chicken interferons.
J. Biol. Chem. 271(13): 7635-7639.

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Cat# ABD11784
(40 western blots)
Availability: Inquire
Bulk Size
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