|Application ||WB, E|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Purified Influenza type B virus (strain B/Tokio/53/99).|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Influenza B antibody, clone IB42 recognizes the nucleoprotein of Influenza virus type B, a genus in the virus family Orthomyxoviridae, responsible for acute respiratory illnesses in humans. Influenza virus type B varies antigenically from influenza virus types A and C and is not divided into any subtypes. The gradual evolution of Influenza virus type B occurs via a series of mutations known as antigenic drift, in the surface glycoprotein haemagglutinin (HA), enabling the virus to evade the immune system and potentially re-infect the same host. HA glycoproteins from the Influenza virus type B are included in the annually updated trivalent flu vaccine, along with the Influenza virus type A subtypes H3N2 and H1N1. Clone IB42 can be used in indirect ELISA and Western Blotting for the serotyping of Influenza virus type B.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Influenza B Antibody, clone IB42 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Hay, A.J. et al. (2001) The evolution of human influenza viruses. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 356: 1861-1870.2. Jackson, D. et al. (2005) Characterization of recombinant influenza B viruses with key neuraminidase inhibitor resistance mutations. J. Antimicro. Chemo. 55: 162-169.
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