|Application ||IHC-F, FC|
|Calculated MW||57825 Da|
|Purification||Purified IgM prepared by ion exchange chromatography|
|Shelf Life||18 months from date of despatch.|
|Other Names||Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54, ICAM1|
|Target/Specificity||Mouse anti-Human CD54 antibody, clone Bu74 recognises human CD54, a ~90 kDa type 1 transmembrane protein which is also known as ICAM-1. CD54 is broadly expressed on haematopoietic and endothelial cells. CD54 is also expressed by many cells following activation by inflammatory mediators. The CD54 molecule is a ligand for integrins CD11a/CD18 and CD11a/CD18, and for fibrinogen. The molecule also acts as a receptor for rhinoviruses and erthyrocytes infected with Plasmodium falciparum.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD54 Antibody, clone Bu74 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Baker, M.P. et al. (1998) Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.Blood. 92 (8): 2830-43. 2. Redchenko, I.V. & Rickinson, A.B. (1999) Accessing Epstein-Barr virus-specific T-cell memory with peptide-loaded dendritic cells.J Virol. 73 (1): 334-42.
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