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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Retinol Binding Protein Antibody, clone G4E4    

Anti-Human Retinol Binding Protein Antibody, clone G4E4

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02753
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names G4E4
Calculated MW 23010 Da
Additional Information
Other Species Rat,Ga,Chimpanzee,M,Rh
Purification Purified IgG prepared by affinity chromatography
Immunogen Human Retinol Binding Protein purified from plasma
Shelf Life 18 months from date of despatch.
Gene ID 5950
Other Names Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176), RBP4
Target/Specificity ABD11803 recognises an epitope within the 74-182 C-terminal (CT) sequence (11kD peptide fragment) of human serum Retinol Binding Protein (RBP), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for the transport of Retinol (vitamin A1) from the liver to peripheral target tissues.RBP is synthesised by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex. An increasing number of studies suggest that the subsequent release of retinol from RBP at the plasma membrane occurs through interaction of RBP with specific membrane receptors.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Retinol Binding Protein Antibody, clone G4E4 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Reddy, B.M. et al. (1993) Antigenic determinants of human serum retinol binding protein as probed with monoclonal antibodies.
Mol. Immunol. 30: 1355-1360.1. Sundaram, M. et al. (1998) The transfer of retinol from serum retinol-binding protein to cellular retinol-binding protein is mediated by a membrane receptor*.
J. Biol. Chem. 273: 3336-3342.

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Cat# ABD11803
(40 western blots)
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