|Calculated MW||28741 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Purified prostate specific antigen|
|Shelf Life||18 months from date of despatch.|
|Other Names||Prostate-specific antigen, PSA, 188.8.131.52, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS|
|Target/Specificity||ABD11812, is specific for prostate specific antigen (PSA) (capture), a 34 kDa member of the Kallikrein subfamily that is secreted in seminal plasma. PSA hydrolyses the seminal vesicle protein, semenogelin-1, which causes the liquefaction of the seminal coagulum. Tumour cell migration is promoted by PSA, furthering the progression of prostate cancer. Latent TGFbeta2 is activated in a process involving PSA, which may contribute to the formation of osteoblastic lesions in bone metastatic prostate cancer. Serum levels of PSA are important in the diagnosis and monitoring of prostatic carcinoma. In addition, levels of PSA in nipple aspirate fluid maybe useful in breast cancer detection.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Prostate Specific Antigen Antibody, clone 58.10D6 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Uludag, Y, et al. (2010) Development of a sensitive detection method of cancerbiomarkers in human serum (75%) using a quartz crystal microbalance sensor and nanoparticles amplification system.Talanta. 82: 277-82. 2. Arya, S.K. and Bhansali, S. (2012) Anti-Prostate Specific Antigen (Anti-PSA) Modified Interdigitated Microelectrode-Based Impedimetric Biosensor for PSA DetectionBiosensors Journal 1: H110601
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