Anti-Feline Immunodeficiency Virus p24 gag Antibody, clone P24CR1
Mouse Anti-Viral Monoclonal Antibody
|Application ||WB, E|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Feline Immunodeficiency Virus p24 gag antibody, clone P24CR1 recognizes a p24 epitope of feline immunodeficiency virus (FIV) p24 gag, distinct from the p24 epitope recognised by clone PAK3-2C1.The lentivirus FIV, responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency Virus (HIV), is a complex retrovirus with a tightly-packed genome, containing the structural genes gag, envandpro-pol and the accessory genes vif, rev and ORF-A/2.Mouse anti-Feline Immunodeficiency Virus p24 gag antibody, clone P24CR1does not recognise Feline Leukaemia Virus (FeLV), Feline Herpes Virus (FHV) type 1, Feline Coronavirus or Feline Calicivirus.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Feline Immunodeficiency Virus p24 gag Antibody, clone P24CR1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Lerner, D.L. et al. (1995) Increased mutation frequency of Feline Immunodeficiency Virus lacking functional deoxyuridine-triphosphatase.Proc. Natl. Acad. Sci. 92: 7480-7484. 2. Celestino, M. et al. (2012) Feline tetherin is characterized by a short N-terminal region and is counteracted by the feline immunodeficiency virus envelope glycoprotein.J Virol. 86: 6688-700.1. Chatterji, U. et al. (2000) Feline Immunodeficiency Virus Vif localises to the nucleus.J. Virol. 74: 2533-2540.2. Norway, R. M. et al. (2001) Thymic lesions in cats infected with a pathogenic molecular clone or an ORF-A/2 -deficient molecular clone of Feline Immunodeficiency Virus.J. Virol. 75: 5833-5841.3. Simon, J.H.M. et al. (1997) The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells. J. Virol. 71: 5259-5267.
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