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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   Anti-Clostridium difficile Toxin A Antibody, clone 5155    

Anti-Clostridium difficile Toxin A Antibody, clone 5155

Mouse Anti-Bacterial Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16154
Reactivity Bacteria
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 5155
Calculated MW 308056 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Clostridium difficile toxin A.
Shelf Life 18 months from date of despatch.
Other Names Toxin A, toxA, tcdA
Target/Specificity ABD11825 is specific for Clostridium difficile toxin A. No reaction is observed with the following organisms:Clostridium difficile toxin B, tetanus toxoid, Pseudomonas aeruginosaandYersinia enterocoliticaClostridium difficile isa gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Clostridium difficile Toxin A Antibody, clone 5155 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Voth, D.E. and Ballard, J.D. (2005) Clostridium difficile toxins: mechanism of action and role in disease.
Clin. Microbiol. Rev. 18: 247-263.

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Cat# ABD11825
(40 western blots)
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