Anti-Human Complement Factor B (BB Fragment) Antibody, clone 10-09
Mouse Anti-Human Monoclonal Antibody
|Application ||WB, IHC-F, FC, E|
|Calculated MW||85533 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Human factor B|
|Shelf Life||18 months from date of despatch.|
|Other Names||Complement factor B, 188.8.131.52, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, BF, BFD|
|Target/Specificity||ABD11836 recognises the Bb fragment of 90 kDa human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Storage at 4℃ or at -20℃.|
|Precautions||Anti-Human Complement Factor B (BB Fragment) Antibody, clone 10-09 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Xu, Y. et al. (2001) Structural biology of the alternative pathway convertase.Immunol. Rev. 180:123-135. 2. Ponnuraj, K. et al. (2004) Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase.Mol. Cell. 14:17-28.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.