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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human Factor P Antibody, clone 10-24    

Anti-Human Factor P Antibody, clone 10-24

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P27918
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 10-24
Calculated MW 51276 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Purified Human factor P from human serum
Shelf Life 18 months from date of despatch.
Gene ID 5199
Other Names Properdin, Complement factor P, CFP, PFC
Target/Specificity ABD11839 recognises human complement factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.ABD11839 does not inhibit function of complement factor P.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Factor P Antibody, clone 10-24 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Hourcade, D. et al. (2006) 1. (2006). The role of properdin in the assembly of the alternative pathway C3 convertases of complement.
J. Biol. Chem. 281:2128-2132. 2. Jelezarova, E. et al. (2000) Interaction of C3b2–IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification.
Biochem. J. 349:217–223.

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Cat# ABD11839
(40 western blots)
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