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>   home   >   Products   >   Primary Antibodies   >   Anti-FK-506 Antibody, clone FK1    

Anti-FK-506 Antibody, clone FK1

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names FK1
Additional Information
Immunogen FK-506-BSA conjugate
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti-FK-506 antibody, clone FK1 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis.FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-FK-506 Antibody, clone FK1 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Letko, E. et al. (1999) Tacrolimus (FK 506).
Ann. Allergy Asthma Immunol. 83: 179-189.

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Cat# ABD11841
(40 western blots)
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