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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human BNP Prohormone (N-Terminal) Antibody, clone 18H5    

Anti-Human BNP Prohormone (N-Terminal) Antibody, clone 18H5

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16860
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 18H5
Calculated MW 14726 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Amino acids 13-27 of NT-proBNP.
Shelf Life 18 months from date of despatch.
Gene ID 4879
Other Names Natriuretic peptides B, Gamma-brain natriuretic peptide, Brain natriuretic peptide 32, BNP(1-32), BNP-32, BNP(1-30), BNP(1-29), BNP(1-28), BNP(2-31), BNP(3-32), BNP(3-30), BNP(3-29), BNP(4-32), BNP(4-31), BNP(4-30), BNP(4-29), BNP(4-27), BNP(5-32), BNP(5-31), BNP(5-29), NPPB
Target/Specificity Mouse anti-Human BNP Prohormone (N-Terminal) antibody, clone 18H5 detects the amino-terminal fragment of pro-brain natriuretic peptide (amino acids 13-20), also known as NT-proBNP, a cleavage product during the proteolytic activation of BNP. NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload. NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human BNP Prohormone (N-Terminal) Antibody, clone 18H5 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Clerico, A. et al. (2006) Clinical relevance of biological variation: the lesson of brain natriuretic peptide (BNP) and NT-proBNP assay.
Clin. Chem. Lab. Med. 44: 366-378.2. Pfister, R. and Schneider, C.A. (2004) Natriuretic peptides BNP and NT-pro-BNP: established laboratory markers in clinical practice or just perspectives?
Clin. Chim. Acta. 349: 25-38.

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Cat# ABD11846
(40 western blots)
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