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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Brain Natriuretic Peptide Antibody, clone 50E1    

Anti-Human Brain Natriuretic Peptide Antibody, clone 50E1

Mouse Anti-Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P16860
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 50E1
Calculated MW 14726 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Human synthetic Brain natriuretic hormone.
Shelf Life 18 months from date of despatch.
Gene ID 4879
Other Names Natriuretic peptides B, Gamma-brain natriuretic peptide, Brain natriuretic peptide 32, BNP(1-32), BNP-32, BNP(1-30), BNP(1-29), BNP(1-28), BNP(2-31), BNP(3-32), BNP(3-30), BNP(3-29), BNP(4-32), BNP(4-31), BNP(4-30), BNP(4-29), BNP(4-27), BNP(5-32), BNP(5-31), BNP(5-29), NPPB
Target/Specificity Mouse anti-Human Brain Natriuretic Peptide antibody, clone 50E1 detects an epitope located at the C-terminal (amino acids 26-32) of the human brain natriuretic peptide (BNP), a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesised as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure.Mouse anti-Human Brain Natriuretic Peptide antibody, clone 50E1 also detects proBNP.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Brain Natriuretic Peptide Antibody, clone 50E1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Clerico, A. et al. (2006) Clinical relevance of biological variation: the lesson of brain natriuretic peptide (BNP) and NT-proBNP assay.
Clin. Chem. Lab. Med. 44: 366-378.2. Pfister, R. and Schneider, C.A. (2004) Natriuretic peptides BNP and NT-pro-BNP: established laboratory markers in clinical practice or just perspectives?
Clin. Chim. Acta. 349: 25-38.

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Cat# ABD11847
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