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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human C7 Antibody, clone 030-    

Anti-Human C7 Antibody, clone 030-

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E, Func
Primary Accession P10643
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 030-
Calculated MW 93518 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Purified human C7.
Shelf Life 18 months from date of despatch.
Gene ID 730
Other Names Complement component C7, C7
Target/Specificity Mouse anti-Human C7 antibody, clone 030- recognises complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides.Mouse anti-Human C7 antibody, clone 030- does not recognie membrane bound complement membrane attack complex.Mouse anti-Human C7 antibody, clone 030- inhibits lysis of sensitised sheep erythrocytes.Removal of Sodium Azide is recommended prior to use in functional assays. AbD Serotec recommend the use of EQU003 for this purpose.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human C7 Antibody, clone 030- is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Langer, F. et al. (2013) Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase.
Blood. 121 (12): 2324-35.1. Thai, C. et al. (2005) Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5.
J. Immunol. 174: 6227-32.2. Debard AL et al. (2005) FcgammaRIIIb and complement component C7 codeficiency in a patient with recurrence of fulminant meningococcal septic shock.
Clin. Infect. Dis. 40: 1679-83.

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Cat# ABD11849
(40 western blots)
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