|Calculated MW||63173 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Purified human C9|
|Shelf Life||18 months from date of despatch.|
|Other Names||Complement component C9, Complement component C9a, Complement component C9b, C9|
|Target/Specificity||ABD11851 recognises complement component 9 (C9), a 71kDa member of the complement C6/C7/C8/C9 family present in the blood serum and synthesised by the liver and monocytes. C9 is the last component to be added during the formation of the membrane attack complex (MAC), binding the membrane associated C5b-8 complex and resulting in the circular polymerisation of 12-18 C9 molecules. This forms the hydrophilic transmembrane channel which causes cell lysis. Deficiency of C9 is associated with recurring infections by Neisseria meningitides.ABD11851 does not recognise MAC.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human C9 Antibody, clone 002-94.8.8 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Huang, Y. et al. (2006) Defining the CD59-C9 binding interaction. J. Biol. Chem. 281:27398-27404.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.