Anti-Respiratory Syncytial Virus Fusion Protein Antibody, clone 0651
Mouse Anti-Viral Monoclonal Antibody
|Application ||IF, E|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Fusion protein of the human Respiratory Synctial Virus.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Respiratory syncitial virus antibody, clone 0651 detects the fusion protein of human respiratory syncytial virus (RSV), groups A and B. RSV is a negative-sense, single-stranded RNA virus and is a member of the Paramyxoviridae family. RSV causes respiratory tract infections in patients of all ages, but particularly affects infants and the immunosuppressed. RSV encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The F protein directs fusion of viral and cellular membranes, resulting in viral penetration, and can lead to the formation of syncytia. The F protein is thought to be the principal antigen responsible for inducing an immune response.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Respiratory Syncytial Virus Fusion Protein Antibody, clone 0651 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Schlender, J. et al. (2003) Respiratory syncytial virus (RSV) fusion protein subunit F2, not attachment protein G, determines the specificity of RSV infection. J. Virol. 77: 4609-4616. 2. Kim, Y.K. et al. (2007) Genetic variability of the fusion protein and circulation patterns of genotypes of the respiratory syncytial virus. J. Med. Virol. 79: 820-828.2. Cianci, C. et al. (2005) Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor. J. Antimicrob. Chemother. 55: 289-292.
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