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Anti-Human C6 Antibody, clone 056B-

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13671
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 056B-
Calculated MW 104786 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Purified human C6
Shelf Life 18 months from date of despatch.
Gene ID 729
Other Names Complement component C6, C6
Target/Specificity ABD11858 recognises complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b–7 precursor complex. C5b–7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection.ABD11858 recognises MAC.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human C6 Antibody, clone 056B- is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. DiScipio, R. et al. (1999) Function of the Factor I modules (FIMS) of human complement component C6.
J. Biol. Chem. 274: 31811-31818.

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Cat# ABD11858
(40 western blots)
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