|Application ||WB, E|
|Calculated MW||14296 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Human Urotensin II|
|Shelf Life||18 months from date of despatch.|
|Other Names||Urotensin-2, Urotensin II, U-II, UII, UTS2|
|Target/Specificity||Mouse anti-Human Urotensin II antibody, clone UII-9 detects Urotensin II (U-II), a cyclic heptapeptide that functions both as a potent vasoconstrictor and a neurotransmitter/neuromodulator. U-II circulates in the plasma as a zymogen, and is activated by the urotensin converting enzyme. U-II is the endogenous ligand for the G-protein coupled receptor 14 (GPR14), recently renamed the UT receptor. Changes in the expression of U-II and its receptor have been associated with cardiovascular and renal diseases, including atherosclerosis, myocardial infarction, and diabetic nephropathy.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Urotensin II Antibody, clone UII-9 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Watanabe, T. et al. (2006) Human urotensin II as a link between hypertension and coronary artery disease. Hypertens. Res. 29: 375-387.2. Nothacker, H.P. and Clark, S. (2005) From heart to mind. The urotensin II system and its evolving neurophysiological role. FEBS J. 272: 5694-5702.3. Zhu, Y.C. et al. (2006) The role of urotensin II in cardiovascular and renal physiology and diseases. Br. J. Pharmacol. 148: 884-901.
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