|Application ||WB, IHC-F, IF, E, IP|
|Calculated MW||64009 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||29 amino acid peptide within the N-terminal catalytic domain of Drosophila AMPK alpha.|
|Shelf Life||18 months from date of despatch.|
|Other Names||5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, 22.214.171.124, Acetyl-CoA carboxylase kinase, ACACA kinase, 126.96.36.199, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, 188.8.131.52, Tau-protein kinase PRKAA1, 184.108.40.206, PRKAA1, AMPK1|
|Target/Specificity||ABD11860 recognises both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK). AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilised by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels.AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-AMPK alpha 1/2 Antibody, clone 84.1 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.