|Application ||WB, E|
|Calculated MW||102486 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant human hexokinase 1 (amino acids 1-917) purified from Escherichia coli.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Hexokinase-1, 22.214.171.124, Brain form hexokinase, Hexokinase type I, HK I, HK1|
|Target/Specificity||Mouse anti-Human hexokinase 1, clone 4D7 recogniszs human hexokinase 1, a 102kDa major allosteric enzyme of the glycolytic pathway, which catalyses the phosphorylation of glucose to form glucose-6-phosphate (Glc-6-P).Hexokinase 1 is the first of four distinct mammalian hexokinase isozymes (hexokinase type 1 to 4), expressed in the outer membrane of mitochondria and is regulated (inhibited) by its product Glc-6-P. A deficiency in hexokinase 1 is implicated in the rare hereditary autosomal recessive disease known as nonspherocytic haemolytic anaemia (Newmanet al.1980).Mouse anti-hexokinase 1, clone 4D7 recognizes an epitope common to all isoforms of human hexokinase.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Hexokinase 1 Antibody, clone 4D7 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Wilson, J.E. (2003) Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function. J. Exp. Biol. 206: 2049-2057.
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